Dr Guy Tsafnat

Contact Details
T:
+612 9850 2430
Bio

PhD (Computer Science and Engineering, UNSW); MSc (Computer Science (machine learning), California State University); BSc (Computer Science (cum laude), California State University)

I am interested in novel computational discovery methods to support biomedical research and clinical decision support systems. I apply knowledge discovery and data mining (KDD), literature based discovery (LBD), formal languages and inference to create tools that support scientific discovery.

My research focuses on how information systems can improve evidence based medicine (EBM) using intelligent algorithms that automate cognitive tasks such as evidence synthesis - drawing a uniform set of conclusions from several clinical trials. Systematic reviews are a critical component of EBM yet 80% are never updated and most are incomplete. The systematic review process can take between 1 and 2 years. The aim of the research is to simplify the tasks undertaken by systematic reviewers through automation. I achieve this aim through innovative research into algorithms, interfaces and tools that accelerate and improve the review process.

In addition I research the identification of appropriate clinical quality indicators to better answer the question of how to measure quality of care efficiently,  accurately and often.

In bioinformatics my research is in DNA sequence modelling using formal languages, with a focus on the genetic mechanisms bacteria use to rapidly evolve resistance to antibiotics.

Broad Research Areas:
Clinical Decision Support Systems, Automation of Evidence Based Medicine, Translational Bioinformatics, Genome Analysis, Antibiotic Resistance

Specific Research Keywords:
Bioinformatics, Translational Research, Computational Discovery, Decision Support Systems, Antibacterial Drug Resistance, Formal Languages, Machine Learning, Literature Based Discovery

Society Memberships & Professional Activities:
American Medical Informatics Association (AMIA), Editorial Board of the Journal of Biomedical Informatics

University role
Senior Research Fellow
Publications

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