Dr Mi Ok Kim

Contact Details
T:
+61 9850 2454
Bio

B. BioMedEng, M. EngSci UNSW, PhD Macquarie University

Dr Mi Ok Kim is a biomedical engineer and postdoctoral research fellow in patient safety team at the Centre for Health Informatics. Her postdoctoral research is focused on investigating evidences for problems that are induced by health IT and their effects on care deliveries and patient outcomes. She also investigates automated surveillance methods such as statistical quality control methods and anomalies detection tools to detect IT problems in healthcare by utilising routinely collected patient data. During her PhD candidature, she worked on developing mathematical models to predict cerebral vascular compliance by utilising pulsatile characteristics of fluid pressure and blood flow in the brain, in order to help diagnose of vascular dementia non-invasively. She is an expert on biomedical signal processing for both of time and frequency domain, and developing predictive algorithms combined with programming skills for efficiently analysing large amounts of data.

Broad Research Areas:
Health IT problems, Patient Safety, Health and Biomedical Informatics, Health Services Research, Data processing, Quantitative analysis, Mathematical modelling

Specific Research Keywords:
Health systems science, Bioinformatics, E-health, Patient Safety

University role
PostDoctoral Research Fellow
Publications

Journal articles

  1. M. Kim, A. Adji, M. O’Rourke, A. Avolio, P.  Smielewski, J. Pickard, M. Czosnyka. Principles of cerebral hemodynamics when intracranial pressure is raised: lessons from the peripheral circulation. J Hypertens 2015 June;33(6):1233-41

  2. M. Golzan, M. Kim, S. Seddighi, A. Avolio, S. Graham. Non-invasive estimation of cerebrospinal fluid pressure waveforms by means of retinal venous pulsatility and central aortic blood pressure. Ann Biomed Eng. 2012 Sep;40(9):1940-8.

Conference papers

  1. M. Kim, M. O’Rourke, A. Avolio, A. Adji. Central pulsatile pressure and flow relationship in time and frequency domain to characterise hydraulic input to the brain and cerebral vascular impedance. Abstract presented as oral communication at ICP and Brain Monitoring 2013 conference, Singapore, and in press for Acta Neurochirurgica Supplement 2014.
  2. M. Kim, A. Adji, M. O’Rourke, A. Avolio, P. Smielewski, J. Pickard, M. Czosnyka. Change in pulsatile cerebral arterial pressure and flow waves as a therapeutic strategy. Abstract presented as poster at ICP and Brain Monitoring 2013 conference, Singapore, and in press for Acta Neurochirurgica Supplement 2014.
  3. M. Kim, P. Eide, M. O’Rourke, A. Avolio, A. Adji. Intracranial pressure waveforms are more closely related to central aortic than radial pressure waveforms: implications to pathophysiology and therapy. Abstract presented as oral communication at ICP and Brain Monitoring 2013 conference, Singapore, and in press for Acta Neurochirurgica Supplement 2014.
  4. M. Kim, J. Li, A. Qasem, S. Graham, A. Avolio. Frequency dependent transmission characteristics between arterial blood pressure and intracranial pressure in rats. Conf Proc IEEE Eng Med Biol Soc. 2012;2012:5614-7.

Conference presentations

  1. M. Kim, Y. Li, F. Wei, J Wang, M. O’Rourke, A. Avolio. Relationship between pressure and flow waveforms in cerebral arteries of 1020 subjects: establishing normal values. Abstract accepted as poster presentation at the American Heart Association Scientific Meeting, November 2014, Chicago, IL, USA.
  2. M. Kim, M. O’Rourke, A. Adji, A. Avolio. Central pulsatile pressure and flow relationship in time and frequency domain to characterise hydraulic input to the brain and cerebral vascular impedance. 15th international symposium on intracranial pressure and brain monitoring 6-10 November 2013, Singapore.
  3. M. Kim, A. Adji, Eide PK, M. O’Rourke, A. Avolio. Intracranial pressure waveforms are more closely related to central aortic than radial pressure waveforms: implication to pathophysiology and therapy. 15th international symposium on intracranial pressure and brain monitoring 6-10 November 2013, Singapore.
  4. M. Kim, M. Butlin, Y. Li, F. Wei, J. Wang, M. O’Rourke, A. Avolio. Contribution of waveform difference between aortic and radial blood pressure pulse in the estimation of cerebral critical closing pressure. 15th international symposium on intracranial pressure and brain monitoring 6-10 November 2013, Singapore.
  5. M. Kim, A. Adji, M. O’Rourke, M. Czosnyka, P. Smielewski, J. Pickard, A. Avolio. Change in pulsatile cerebral arterial pressure and flow waves as a therapeutic strategy. 15th international symposium on intracranial pressure and brain monitoring 6-10 November 2013, Singapore
  6. M. Kim, M. Butlin, Y. Li, F. Wei, J. Wang, M. O’Rourke, A. Avolio. Aortic, but not radial pressure gives a model independent estimate of cerebral artery critical closing pressure.  Artery 2013, October 17-19, London, UK
  7. M. Kim, Y. Li, F. Wei, J. Wang, M. O’Rourke, A. Avolio. Influence of wave reflection and lower body properties on cerebral perfusion in apparently normal human subjects. 23rd European meeting on hypertension and cardiovascular protection 14-17 June, 2013, Milan, Italia.
  8. M. Kim, A. Adji, Y. Li, F. Wei, J. Wang, M. O’Rourke, A. Avolio. Pulsatility of pressure and flow waveforms in cerebral arteries: origin and significance. Scientific sessions 2012 American Heart Association 4-6 Nov, 2012, Los Angeles, United States.
  9. M. Kim, A. Adji, Y. Li, F. Wei, J. Wang, M. O’Rourke, A. Avolio. The vis-a-tergo for cerebral perfusion: role of the left ventricle and systemic arteries and implications for therapy in stroke. 24th Scientific Meeting of the International Society of Hypertension (ISH), 30 Sep – 4 Oct, 2012; Sydney, Australia
  10. M. Kim, A. Adji, Y. Li, F. Wei, J. Wang, M. O’Rourke, A. Avolio.  Pulsatile pressure/flow relations in human cerebral arteries, described in time and frequency domain as vascular impedance. 24th Scientific Meeting of the International Society of Hypertension (ISH) , 30 Sep – 4 Oct, 2012; Sydney, Australia
  11. A. Adji, M. Kim, M. Czosnyka, P. Smielewski, J. Pickard, M. O’Rourke. Change in pulsatile cerebral arterial pressure and flow waves as a therapeutic target. 24th Scientific Meeting of the International Society of Hypertension (ISH), 30 Sep – 4 Oct, 2012; Sydney, Australia
  12. M. Kim, J. Li, A. Qasem, S.L. Graham, A. Avolio. Frequency dependent transmission characteristics between arterial blood pressure and intracranial pressure in rats. 34th Annual international conference of the IEEE Engineering in Medicine & Biology Society (EMBS) 28 Aug – 1st Sep 2012; San Diego, United States of America.
  13. A. Adji, M. Kim, M. O’Rourke, A. Avolio, P.K. Eide. Relationship between central pulsatile aortic and intracranial pressure in humans. European Society of Hypertension (ESH) 2012: 22nd European Meeting on Hypertension and Cardiovascular Protection, April 26-29, 2012;London, United Kingdom
  14. M. Kim, J. Li, A. Qasem, S.L. Graham, A. Avolio. Selective frequency attenuation in transmission characteristic between arterial blood pressure and intracranial pressure. European Society of Hypertension (ESH) 2012: 22nd European Meeting on Hypertension and Cardiovascular Protection, April 26-29, 2012;London, United Kingdom
  15. A. Avolio, M. Kim, M. Golzan. Central aortic blood pressure and intracranial pressure World Hypertension League Regional Congress (2011), Beijing, China
  16. M. O’Rourke, A. Adji, M. Kim, M. Czosnyka, P. Smielewski, J. Pickard. Change in pulsatile central cerebral arterial pressure and flow waves as a therapeutic target against secondary brain damage following trauma.  AHA 2011
  17. A. Adji, M. Kim, M. O’Rourke, A. Avolio. Relationship between central pulsatile aortic pressure and middle cerebral artery flow waveforms in normal young adults. 2011Annual Scientific Meeting of High Blood Pressure Research Council of Australia, Perth, Australia
  18. A. Adji, M. Kim, M. O’Rourke, A. Avolio, P.K. Eide. Relationship between central pulsatile aortic and intracranial pressure in humans. 2011Annual Scientific Meeting of High Blood Pressure Research Council of Australia, Perth, Australia
  19. M. Kim, A. Avolio, P.K. Eide, A. Qasem. Non-invasive estimation of intracranial pulse pressure from the central aortic pressure waveform.  2011Annual Scientific Meeting of High Blood Pressure Research Council of Australia, Perth, Australia
  20. M. Kim, A. Avolio, Y. Li, P.K. Eide. Non- invasive assessment of cerebral compliance from central aortic pressure: comparison in normotensive, hypertensive and normal pressure hydrocephalus subjects. The 21st meeting on Hypertension and Cardiovascular prevention (2011), Milan, Italy
  21. M. Kim, A. Avolio. Non-invasive estimation of cerebral arterial cross sectional compliance. 2010 Annual Scientific Meeting of HBPRCA, Melbourne, Australia
  22. A. Avolio, M. Butlin, M. Kim, A. Qasem, S.L. Graham. Central Aortic Pressure and Assessment of End Organ Function. Australia J HK Coll Cardiol, Vol 18/ Number1 p30, 2010
  23. M. Kim, A. Avolio. Non-invasive estimation of intracranial compliance from the arterial pressure waveform. 14th international conference on Intracranial Pressure and Brain Monitoring 2010, Tubingen, Germany.
  24. M. Kim, A. Avolio. Non-invasive estimation of indices of cerebral vascular compliance. The 23rd Scientific Meeting of International Society of Hypertension, Vancouver, Canada. 2010
  25. M. Kim, A. Qasem, A. Avolio. Non-invasive estimation of cerebral critical closing pressure. The 23rd Scientific Meeting of International Society of Hypertension, Vancouver, Canada. 2010
  26. M. Kim and A. Avolio. Effect on time delay between pressure and flow signals on calculation of cerebral critical closing pressure and resistance area product. 2009 Annual Scientific Meeting of High Blood Pressure Research Council of Australia, Sydney, Australia
  27. M. Kim and A. Avolio Non-invasive estimation of cerebral critical closing pressure from Transcranial Doppler flow and peripheral and central pressure pulse.EPSM-SMBE 2009, Canberra, Australia

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